DNA Next Generation sequencing is a powerful, although not fully new technique for understanding genomes and transcriptomes of species. With each sample requiring multiple gigabytes of storage, analysing the DNA patterns becomes challenging. This is the reason behind the invention of the burrows wheeler algorithm, which reduces the time of analysis to the order of 10^(-4). This is not a new algorithm, but newer iterations are being built using this as the base, which is why it is important to understand the algorithm.
Understanding how DNA sequence data is depicted and stored. How the algorithm works. How this information can be used to conduct bioinformatics research.